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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX59
All Species:
33.03
Human Site:
T249
Identified Species:
48.44
UniProt:
Q5T1V6
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1V6
NP_001026895.2
619
68810
T249
D
I
L
A
S
A
D
T
G
S
G
K
T
A
A
Chimpanzee
Pan troglodytes
XP_001143546
619
68778
T249
D
I
L
A
S
A
D
T
G
S
G
K
T
A
A
Rhesus Macaque
Macaca mulatta
XP_001109688
319
35696
Dog
Lupus familis
XP_537128
620
68704
T250
D
V
L
A
S
A
D
T
G
S
G
K
T
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBN9
619
68216
T249
D
I
L
A
S
A
D
T
G
S
G
K
T
A
A
Rat
Rattus norvegicus
Q66HG7
589
65047
T249
D
I
L
A
S
A
D
T
G
S
G
K
T
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520980
538
59378
C219
G
F
P
E
T
L
N
C
N
L
K
K
S
G
Y
Chicken
Gallus gallus
XP_422189
625
69278
T255
D
I
V
A
S
A
D
T
G
S
G
K
T
A
A
Frog
Xenopus laevis
NP_001106297
254
27959
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
T391
A
K
T
G
S
G
K
T
I
A
F
L
L
P
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
T291
D
L
M
A
C
A
Q
T
G
S
G
K
T
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198909
620
68882
D259
D
T
A
E
D
A
E
D
A
A
D
V
A
A
T
Poplar Tree
Populus trichocarpa
XP_002320399
524
57616
L205
K
K
P
L
A
M
V
L
T
P
T
R
E
L
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3EBD3
505
55199
N186
H
P
S
D
Q
R
R
N
P
L
A
M
V
L
A
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
S233
E
K
A
Q
S
F
Y
S
R
K
G
Y
P
S
A
Red Bread Mold
Neurospora crassa
Q7SEL0
728
82594
T339
D
L
I
G
V
A
V
T
G
S
G
K
T
A
A
Conservation
Percent
Protein Identity:
100
99
51
89.8
N.A.
83.6
79.8
N.A.
61.8
72.3
30.2
22.3
N.A.
27.6
N.A.
N.A.
32.1
Protein Similarity:
100
99.8
51.3
93.3
N.A.
89.6
86.7
N.A.
71.5
84.3
35.3
37.3
N.A.
45.8
N.A.
N.A.
52.4
P-Site Identity:
100
100
0
93.3
N.A.
100
100
N.A.
6.6
93.3
0
13.3
N.A.
73.3
N.A.
N.A.
20
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
26.6
100
0
20
N.A.
86.6
N.A.
N.A.
33.3
Percent
Protein Identity:
40.7
N.A.
N.A.
38.1
26.3
26.9
Protein Similarity:
58
N.A.
N.A.
56.2
46.3
46.4
P-Site Identity:
0
N.A.
N.A.
6.6
20
66.6
P-Site Similarity:
13.3
N.A.
N.A.
6.6
40
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
13
44
7
57
0
0
7
13
7
0
7
57
63
% A
% Cys:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
7
% C
% Asp:
57
0
0
7
7
0
38
7
0
0
7
0
0
0
0
% D
% Glu:
7
0
0
13
0
0
7
0
0
0
0
0
7
0
0
% E
% Phe:
0
7
0
0
0
7
0
0
0
0
7
0
0
0
0
% F
% Gly:
7
0
0
13
0
7
0
0
50
0
57
0
0
7
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
32
7
0
0
0
0
0
7
0
0
0
0
0
0
% I
% Lys:
7
19
0
0
0
0
7
0
0
7
7
57
0
0
0
% K
% Leu:
0
13
32
7
0
7
0
7
0
13
0
7
7
13
0
% L
% Met:
0
0
7
0
0
7
0
0
0
0
0
7
0
0
7
% M
% Asn:
0
0
0
0
0
0
7
7
7
0
0
0
0
0
0
% N
% Pro:
0
7
13
0
0
0
0
0
7
7
0
0
7
7
0
% P
% Gln:
0
0
0
7
7
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
7
0
7
0
0
7
0
0
0
% R
% Ser:
0
0
7
0
50
0
0
7
0
50
0
0
7
7
0
% S
% Thr:
0
7
7
0
7
0
0
57
7
0
7
0
50
0
7
% T
% Val:
0
7
7
0
7
0
13
0
0
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _